ODCs

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2 OMIM references -
2 associated genes
13 signs/symptoms

PROTEIN INTERACTIONS: 1

1 OMIM reference -
2 associated genes
4 signs/symptoms

Peripheral resistance to thyroid hormones

Myxoid/round cell liposarcoma

THRA	(UniProt - OMIM)		DDIT3	(UniProt - OMIM)
THRB	(UniProt - OMIM)		FUS	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	THRA	(0.85)	FUS

Citations in the biomedical literature:

Peripheral resistance to thyroid hormones		Myxoid/round cell liposarcoma
	Synonym(s): (no synonyms)		Synonym(s): - MRCLS

	Classification (Orphanet): - Rare endocrine disease - Rare genetic disease		Classification (Orphanet): - Rare oncologic disease

	Classification (ICD10): - Endocrine, nutritional and metabolic diseases -		Classification (ICD10): - Neoplasms -

	Epidemiological data: (no data available)		Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: adult Type of inheritance: sporadic

	External references: 2 OMIM references - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: D018208

Peripheral resistance to thyroid hormones		Myxoid/round cell liposarcoma
	Very frequent - Absent / hypotonic / flaccid abdominal wall muscles - Autosomal dominant inheritance - Coarse face - Constipation - Face / facial anomalies - Failure to thrive / difficulties for feeding in infancy / growth delay - Hepatitis / icterus / cholestasis - Hypothyroidy - Hypotonia - Large fontanelle / delayed fontanelle closure - Macroglossia / tongue protrusion / proeminent / hypertrophic - Sleep and vigilance disorders - Umbilical hernia		Very frequent - Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma - Subcutaneous nodules / lipomas / tumefaction / swelling Occasional - Acute abdominal pain / colic - Intestinal transit disorder